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Screen negative results

A screen negative result means that the risk of the baby being affected by Down syndrome or trisomy 18 is less than the cut-off.  For example, the screen cut-off for Down syndrome with the Integrated Prenatal Screen is 1 in 200.  Therefore, any result, lower than 1 in 200 is considered screen negative.  The screen cut-off varies between screens and conditions.
A screen negative test can be reassuring but it is not diagnostic.  Therefore, it is important to communicate that a screen negative test does not rule out the chance for the baby to have one of these conditions; a screen negative test can reduce the risk but does not eliminate it.
ALL pregnancies have a 2-3% risk for any birth defect wich may or may not be detected by prenatal screening.